The New Therapies Challenge Research Teams are the first projects funded under the Pancreatic Cancer Collective, a strategic partnership of Lustgarten Foundation and Stand Up To Cancer, to accelerate pancreatic cancer research and improve patient outcomes for pancreatic cancer, which is one of the deadliest cancers. The Challenge represents a new, focused effort to increase the number of innovative and effective therapies to treat pancreatic cancer. Collaborative, multi-disciplinary teams are being supported to investigate novel or repurposed medicines, treatment strategies, or technologies that have the potential to significantly impact pancreatic cancer patients in the near term. The New Therapies Challenge involves a two-step approach that provides initial, short-term funding to a number of applicants (Round 1), followed by additional funding for a subset of Round 1-funded Teams (Round 2) for clinical studies. Seven projects received Round 1 funding in November 2018.