BRAINatomy: A Validated Anatomical Atlas of Childhood Neuroradiation Damage - Stand Up To Cancer

Research Teams

Research  >  Research Portfolio  >  Research Teams  >  BRAINatomy: A Validated Anatomical Atlas of Childhood Neuroradiation Damage

SU2C-CRUK Pediatric Cancer New Discoveries Challenge:
BRAINatomy: A Validated Anatomical Atlas of Childhood Neuroradiation Damage

Grant Term: April 2021-March 2023

The SU2C-CRUK Pediatric Cancer New Discoveries Challenge is a new, focused effort to spark novel approaches and new collaborations from investigators both within and outside the field of pediatric cancer research, with the ultimate aim of increasing the number of innovative and effective approaches to treating pediatric cancers. This program will support collaborative, multi-disciplinary, multi-institutional, trans-Atlantic Teams to pursue a transformative change in our understanding of the drivers of pediatric cancers and the development of novel or repurposed medicines, treatment strategies or technologies. With a clear and rational line of sight to the clinic, these projects will have the potential to significantly impact pediatric cancer patients, including teenagers and young adults.


Precision radiotherapy is currently an essential part of the treatment of many pediatric brain tumors. However, even with improvements in the targeting of the radiation, these treatments can still cause lifelong side effects on cognition and hormone production. This Team is proposing to study the path the radiation travels in treating pediatric brain tumors, comparing pre- and post-treatment in order to link brain regions to long term side effects. This project will allow the Team to identify the regions of the brain that are sensitive to radiation and involved in cognition and hormone production, in order to develop an atlas of brain regions to be avoided during radiotherapy.


Pediatric New Therapies Challenge Overview


Sign up to receive emails from Stand Up To Cancer.
   Please leave this field empty
Please validate the captcha
Stand Up to Cancer

Thanks for signing up!
You will hear from us soon.